Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine and bloating Hydroxychloroquine long term To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed length of time for malaria. Those who are newly diagnosed with lupus may take 400 mg once daily for several weeks while the medication builds up in their system, and then 200–400 mg daily after that. To lower the daily dosage, to adjust for low weight, or if there is kidney damage or kidney failure, HCQ may be taken every other day or tablets may be broken in half. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil pill dosage Hydroxychloroquine Oral Tablet 200Mg Drug Medication., Drug spotlight on hydroxychloroquine Lupus Foundation of. What does hydroxychloroquine do to the bodyPlaquenil and general anesthesiaHow effective is chloroquinePlaquenil side effects anti depressantsAdministration with chloroquine The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. For treatment of acute attacks of malaria in adults, four tablets are usually taken right away, followed by two tablets 6 to 8 hours later and then two tablets on each of the next 2 days. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil Dosage Guide -. Hydroxychloroquine Plaquenil. Plaquenil Hydroxychloroquine may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Following a single 200 mg oral dose of PLAQUENIL to healthy males, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus.