Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus (SLE or "Lupus") and rheumatoid arthritis. Although chloroquine is sometimes used, the preferred antimalarial drug is hydroxychloroquine due to its greater safety. It is not possible at the present time to explain precisely why hydroxychloroquine is effective in various rheumatic diseases. I take 2 hydroxychloroquine Hydroxychloroquine enhance of inhibit immune Treatment of discoid lupus erythematosus with chloroquine Lupus anticoagulants occur in about 5% to 10% of patients with systemic lupus erythematosus. They block the in vitro assembly of the prothrombinase complex, resulting in a prolongation of protein assays such as activated partial thromboplastin time, dilute Russell viper venom time, kaolin plasma clotting time, and, rarely, prothrombin time. Alternatively known as antiphospholipid antibody syndrome, lupus anticoagulant syndrome is a coagulation disorder which causes formation of thrombosis in blood vessels. This condition is attributed to the autoimmune antibody production against a particular phospholipid known as cardiolipin. For some people with very mild lupus, NSAIDs alone are enough to control symptoms. Antimalarial drugs. Hydroxychloroquine Plaquenil is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. Hydroxychloroquine is a tablet that is best taken with food as it has a slightly bitter taste. When effective, it can decrease damage to the tissues of the joints, skin and other organs in the body. Plaquenil and lupus anticoagulant Plaquenil. A medication for Lupus, Lupus Anticoagulant Syndrome - Symptoms, Treatment. Plaquenil rebateCalcium autophagy chloroquine Hydroxychloroquine Plaquenil is an antimalarial medication, which is used to treat systemic lupus erythematosus SLE, also known as lupus. Hydroxychloroquine has anti-inflammatory effects and also inhibits platelet clumping, which is a key step in blood clot formation. Antiphospholipid Syndrome and Potential New Treatments HSS. Lupus Medications and Treatments. Anti-phospholipid Antibody Testing Lupus Anticoagulant Testing. Recently the lovely Nurse on here mentioned Lupus Anticoagulant factor which I'm now under investigation for. Apparantly it causes MC in 85% of Lupus ladies and the treatment is simple. If you have Lupus symptoms get your doctor to refer you to a Consultant that specialises in Lupus, my blood tests don't always show any inflammatory. Antiphospholipid antibodies aPL Abs play an active role in the pathogenesis of the antiphospholipid syndrome APLS. Primary prevention in APLS may be aimed at decreasing existing elevated aPL Ab levels, or preventing high aPL titers and/or lupus anticoagulant LAC from developing in the first place. The antiphospholipid aPL syndrome APS is an acquired autoimmune thrombophilic condition that is a cause of pregnancy complications attributable to placental insufficiency including recurrent pregnancy losses and other including IUGR, oligohydramnios, preeclampsia/toxemia and placental abruption.