Carole, Just curious, did you try the generic (hydroquix...)or brand name Plaquenil? When I started Plaquenil, my GI system was in an uproar. I couldn't tolerate the generic, but the brand name has a coating for the stomach. Imuran and plaquenil t Plaquenil for pain control Take plaquenil morning or night My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. arthritis, alternative, remedies, rheumatoid, glenn, frey. In some cases, they may not be available in every strength or form as the brand-name drug. Wallace's book and found the stats, plus my rheumie telling me much the same, that many people with lupus (something like 40% or more) "present" with GI problems. Meaning long enough to start to sort out whether your problems were mainly from the disease or from the med? Substitute for hydroxychloroquine What can substitute plaquenil hydroxychloroquine., Hydroxychloroquine Plaquenil Side Effects & Dosage for. Hydroxychloroquine and pregnancyPlaquenil and tylenolVoltaren pills vs plaquenil If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Common and Rare Side Effects for Hydroxychloroquine Oral. Safe, Natural Alternatives to Arthritis Drugs Top Doc.. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Is there a drug that I can take to replace plaquenil? Asked by tanner01 Updated 5 April 2018 Topics plaquenil, rheumatoid arthritis, methotrexate. I take methotrexate also but the plaquenil messed with my vision and I had to quit taking it. I been treated for ra for 19 yrs. And I'm beginning to see more changes in my feet and hands.