It seems as though it has helped the first two symptoms, but I have horrible constipation. Lots of people experience some GI issues when starting Plaquenil, but they usually subside after a short time. I have tried everything- I exercise every day, drink a ton of water, eat fiber like it’s going out of style, follow a gluten-free diet, take stool softeners after every meal and Miralax before bed at night. Did you start Plaquenil when you rec'd your diagnosis and did the constipation begin at the same time? Quinoric or plaquenil Urinary side effects of hydroxychloroquine Plaquenil and ibuprofen together Plaquenil lupus nephritis treatment guidelines Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. I started Plaquenil in Feb. I'm anti meds but the time came to try improve quality of my life. The side effects in the 1st week were amplified fatigue & nausea for a good month. I kept taking them & now I don't have any side effects. My energy much better, no more daytime napping needed optition side the retina toxification is very rare. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. I have intermittent problems with constipation and take Miralax at times - and feel that it sometimes causes bloating. I have really bad cramping, gas and it looks like I’m 7 months pregnant at times! I think it might be possible that the constipation could have something to do with the Lupus, as it can affect the GI tract also. Bad side effects of hydroxychloroquine Hydroxychloroquine Oral Route Precautions - Mayo Clinic, How good is Hydroxychloroquine, and any side effe. Plaquenil side effects sunlightMalarone plaquenil interaction Side effects of hydroxychloroquine. The adverse effects of this drug canappear in combination or alone, and usuallythey occur when the medicine is used for a long period of time. Of ocular side effects, the mostfrequent is blurred vision. Side effects of hydroxychloroquine General center.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects. I have been recently diagnosed with Lupus about 4 months ago and have started plaquenil with the hope it would relieve my symptoms no energy, achy body and severe hair loss. It seems as though it has helped the first two symptoms, but I have horrible constipation. I have tried everything- I exercise every day, drink a ton of water, eat fiber like it’s going out of style, follow a gluten. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects.