Chloroquine and receptor mediated endocytosis

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  1. alexMaks Well-Known Member

    Chloroquine and receptor mediated endocytosis


    Detailed information on how Wiley uses cookies can be found in our Privacy Policy. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it.

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    In receptor-mediated endocytosis, the cell will only take in an extracellular molecule if it binds to its specific receptor protein on the cell’s surface. Once bound, the coated pit on which the bound receptor protein is located then invaginates, or pinches in, to form a coated vesicle. Similar to the digestive process in non-specific. The LDL receptor gene a mosaic of exons shared with different proteins. Science. 1985 May 17; 228 4701815–822. PMC free article Tietze C, Schlesinger P, Stahl P. Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages apparent inhibition of receptor recycling. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. It is taken by mouth. Common side effects include muscle problems, loss of appetite, diarrhea, and skin rash. Serious

    It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance.

    Chloroquine and receptor mediated endocytosis

    In Vivo Evidence That Cobalamin Is Absorbed by Receptor., Receptor-mediated endocytosis.

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  4. Jun 01, 2009 As clathrin-dependent endocytosis is known to be involved in TGFβ-induced signaling, we wished to determine the effects of known inhibitors of clathrin-dependent endocytosis on internalization of cell-surface-bound TGFβ in Mv1Lu cells.

    • Inhibitors of clathrin-dependent endocytosis enhance TGFβ..
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    Caveolae is similar to receptor-mediated endocytosis, but the vesicles are not coated in clathrin, but another transport membrane protein called caveolin. They are small bottle-shaped vesicles waiting below the cellular membrane and serve a similar function as the clathrin-coated pits. Feline calicivirus FCV is a major causative agent of respiratory disease in cats. FCV infects cells via clathrin‐mediated endocytosis. Inhibitors of endosome acidification such as chloroquine block the viral permeabilization event in endosome Stuart and Brown 2006. Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages Apparent inhibition of receptor recycling Author links open overlay panel Christopher Tietze Paul Schlesinger Philip Stahl

     
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    The NICE Clinical Knowledge Summaries (CKS) site is only available to users in the UK, Crown Dependencies and British Overseas Territories. PATIENT FACT SHEET Hydroxychloroquine Plaquenil Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening
     
  7. Plaquenil Hydroxychloroquine Side effects, Images, Uses, Dosage. What should I avoid while taking hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Some antacids can make it harder for your body to absorb hydroxychloroquine.

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