I developed congestive heart failure and was taken off all RA meds except prednisone for a year. For years, I have been complaining to any of my doctors, who would listen, about the dizziness. I went back to my rheumatologist and he prescribed plaquenil again. In the beginning ( The first year or two) It really helped, with my symptoms, with lupus. This past two years, the dizziness has now, turned in to vertigo. What is plaquenil for lupus Plaquenil kidney pain Hydroxychloroquine side effects heart ef 25 Plaquenil action I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. BUT after being off it for a month and a half my body feels like it's falling apart. Renal clearance in rheumatoid arthritis RA patients taking Plaquenil for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. How to tell if the drug is working For rheumatoid arthritis, you should have reduced joint inflammation and you should be able to move better within 6 months of starting the medication. For lupus. Now, that I have read this site, explanation of plaquenil, I think the mystery is solved. After taking it for 6 weeks, I had shortness of breath so I stopped taking it. Again, I have been trying to find out , what have been causing the vertigo. Plaquenil 6 months Hydroxychloroquine Plaquenil, Plaquenil - FDA prescribing information, side effects and uses Hypnozoite chloroquine resistancePlaquenil and low blood pressure Immunodeficiency disorders is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Mixed connective tissue disease. Will you have Immunodeficiency disorders with Plaquenil.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil oral Reviews and User Ratings Effectiveness.. Taking Plaquenil. Plaquenil is available in 200 mg oral tablets. The usual dose is between one and two tablets per day 200 to 400 mg per day. When Plaquenil works, most patients start to feel improvement after 8-12 weeks. The maximum effect can take 6-12 months. I love plaquenil too and just hit the sixth month mark 400mg a day. It took about 3 months for me to notice anything, but seems to get better and better the longer I'm on it. Still getting the flares, but they don't seem to be as severe as they were now. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few.