Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine ingredients Endometriosis plaquenil Plaquenil and smoking Plaquenil for lichen planus Subretinal Drusenoid Deposits In Non-Neovascular Age-Related Macular Degeneration Morphology, Prevalence, Topography, And Biogenesis Model. Luibl V, Isas JM, Kayed R, et al. Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers. Sep 04, 2007 Well I had my regular ophthalmology appointment today and the doc said he sees drusen in my eye. He said that its a pre-sign to macular degeneration which can lead to partial blindness. Because of my age I'll be 32 this month it is very rare. Thing is he didn't see it back in January when I went for my baseline appt before starting Plaq. Drusen Deposits in the Eye Drusen are small yellow or white deposits that form in the retina or on the optic nerve head. They are accumulations of extracellular material that build up in the eye. The detection of a few drusen is normal with aging eyes, with most people over the age of 40 having at least some drusen. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil drusrn deposits Drusen-like Deposits in Young Adults Diagnosed With Systemic., Drusen in my retina - What happens if i overdose on celecoxib and plaquenilItp plaquenil Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so. Protecting your eyesight when taking Plaquenil Lupus.. Drusen Deposits in the Eye -. Maculopathy Causes and Symptoms - Micro Chirurgia Oculare. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Macular drusen are yellow deposits that develop between the retinal pigment epithelium and the choroid layer – the layer of blood vessels that supply nutrients to the macula. There are many factors that lead to the development of AMD, but one of them is the inability of the macula to get rid of waste products or to get oxygen rich nutrients from the underlying tissue. Dr. Marmor’s research team also recommended that screening should be performed within the first year of initiating therapy, and then annually after five years of Plaquenil use. The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g.