Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people. 2006;368(9529):29-3616815377Google Scholar Crossref Crandall J, Schade D, Ma Y. The influence of age on the effects of lifestyle modification and metformin in prevention of diabetes. 2006;61(10):1075-108117077202Google Scholar Crossref Gerstein HC, Yusuf S, Bosch J. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. 2006;368(9541):1096-110516997664Google Scholar Crossref Kitabchi AE, Temprosa M, Knowler WC. Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. 2005;54(8):2404-241416046308Google Scholar Crossref Emami J, Pasutto FM, Mercer JR, Jamali F. Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. 1999;64(5):325-33510072192Google Scholar Crossref Emami J, Gerstein HC, Pasutto FM, Jamali F. Plaquenil drug side effects Methotrexate and plaquenil for ra Whhat kind of damage does plaquenil cause to the eye Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Hydroxychloroquine Sulfate “Plaquenil” in Treatment of Rheumatoid Arthritis By E. B. D. HAMILTON AND J. T. SCOTT A controlled therapeutic trial in 41 pa- tients comparing hydroxychloroquine Plaquenil and a placebo tablet showed a small but statistically significant dif- ference in favor of hydroxychloroquine As for malaria treatment, though Plaquenil can be indicated for the treatment of uncomplicated malaria, the exact mechanism by which this drug works to resolve malaria is largely unknown. Mode of action of chloroquine in patients with non-insulin-dependent diabetes mellitus. 1991;260(6 Pt 1): E897-E9042058666Google Scholar Quatraro A, Consoli G, Magno M. Hydroxychloroquine in decompensated, treatment-refractory noninsulin-dependent diabetes mellitus: a new job for an old drug? 1990;112(9):678-6812110430Google Scholar Crossref Arnett FC, Edworthy SM, Bloch DA. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. 1988;31(3):315-3243358796Google Scholar Crossref Krishnan E, Tugwell P, Fries JF. Insulin-sparing effect of hydroxychloroquine in diabetic rats is concentration dependent. 1999;77(2):118-12310535702Google Scholar Crossref Powrie JK, Smith GD, Shojaee-Moradie F, Sonksen PH, Jones RH. Of dropout in rheumatoid arthritis treatment with hydroxychloroquine PATIENT FACT SHEET Hydroxychloroquine Plaquenil, Hydroxychloroquine sulfate â Plaquenilâ in treatment of. Hydroxychloroquine arthritis forumEffects of plaquenil rx on osteoarthritisPlaquenil ibuprofen interactionChloroquine phosphate synthesis Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. RA and Hydroxychloroquine How Effective is it for Rheumatoid.. What Exactly Is Hydroxychloroquine, The Drug That Is Being.. Recommendations of the Brazilian Society of Rheumatology.. Rated Hydroxychloroquine for Rheumatoid Arthritis Report Plaquenil was a miracle drug for me. It began to work in 3 weeks and within 6 months my inflammation had gone from over 40 to 5.5. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used.