So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Plaquenil dx code Who should take plaquenil I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Chances of having a lupus flare when stopping plaquenil Stopping Plaquenil - General Discussion - Life With Lupus, The Risk of Retinal Toxicity with Plaquenil Chloroquine doxycyclinePlaquenil usoSide effects of plaquenil on eyes Don't stop to dwell on or judge your thoughts. Understand that infections can cause a lupus flare. If you have an infection of any sort, your chances of having a lupus flare increase. This is because viral or bacterial infections attack the immune system; this attack can trigger the flare. Ways to Handle a Lupus Flare - wikiHow. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Lupus Flare - How Will You Know If You Are Having A Flare?. Because previous studies have found strong connections between Plaquenil and decreased lupus flares, the amount of damage to the body, and the favorable impact on survival, the researchers deemed it to be unethical to conduct a double-blind, placebo study. Instead, the researchers used statistical models to create two groups based on the. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. I have taken plaquenil for lupus off and on for two years one day I started having panic attacks I stopped caffeine alcohol etc. The only thing that helped was stopping the plaquenil after feeling better and some time I thought I’d try it again after a flare.